Principle: A tool for associating genes with diseases via network propagation

Assaf Gottlieb; Oded Magger; Igor Berman; Eytan Ruppin; Roded Sharan

doi:10.1093/bioinformatics/btr584

Principle: A tool for associating genes with diseases via network propagation

Assaf Gottlieb, Oded Magger, Igor Berman, Eytan Ruppin, Roded Sharan

School of Computer Science

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein-protein interaction network to genes causing phenotypically similar disorders to the query disease.

Original language	English
Article number	btr584
Pages (from-to)	3325-3326
Number of pages	2
Journal	Bioinformatics
Volume	27
Issue number	23
DOIs	https://doi.org/10.1093/bioinformatics/btr584
State	Published - Dec 2011

All Science Journal Classification (ASJC) codes

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

Access to Document

10.1093/bioinformatics/btr584

Cite this

@article{ce3208c660514df9ab97c1050494ea12,

title = "Principle: A tool for associating genes with diseases via network propagation",

abstract = "PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein-protein interaction network to genes causing phenotypically similar disorders to the query disease.",

author = "Assaf Gottlieb and Oded Magger and Igor Berman and Eytan Ruppin and Roded Sharan",

note = "Funding Information: Funding: Edmond J. Safra bioinformatics program (to A.G.); Bikura grant from the Israel Science Foundation (to E.R. and R.S.).",

year = "2011",

month = dec,

doi = "10.1093/bioinformatics/btr584",

language = "الإنجليزيّة",

volume = "27",

pages = "3325--3326",

journal = "Bioinformatics",

issn = "1367-4803",

publisher = "Oxford University Press",

number = "23",

}

TY - JOUR

T1 - Principle

T2 - A tool for associating genes with diseases via network propagation

AU - Gottlieb, Assaf

AU - Magger, Oded

AU - Berman, Igor

AU - Ruppin, Eytan

AU - Sharan, Roded

N1 - Funding Information: Funding: Edmond J. Safra bioinformatics program (to A.G.); Bikura grant from the Israel Science Foundation (to E.R. and R.S.).

PY - 2011/12

Y1 - 2011/12

N2 - PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein-protein interaction network to genes causing phenotypically similar disorders to the query disease.

AB - PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein-protein interaction network to genes causing phenotypically similar disorders to the query disease.

UR - http://www.scopus.com/inward/record.url?scp=82255185475&partnerID=8YFLogxK

U2 - 10.1093/bioinformatics/btr584

DO - 10.1093/bioinformatics/btr584

M3 - مقالة

SN - 1367-4803

VL - 27

SP - 3325

EP - 3326

JO - Bioinformatics

JF - Bioinformatics

IS - 23

M1 - btr584

ER -

Principle: A tool for associating genes with diseases via network propagation

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this