Presence of Periopathogens in Sinus Floor Augmentation Sites: A Cohort Study

Yifat Manor, Ilan Beitlitum, Alex Manor, Ronit Bar Ness Greenshtein

Research output: Contribution to journalArticlepeer-review


Purpose: To investigate the effects of periopathogens on bone grafts for maxillary sinus floor augmentation and implant survival. Materials and Methods: A cohort study was designed. Samples from maxillary sinus floor augmentation sites and from periodontal pockets in adjacent teeth of the same patients were collected during the surgery and following periodontal maintenance and plaque removal. Polymerase chain reaction (PCR) was performed by an external lab service for analysis of the following periopathogens: Aggregatibacter actinomycetemcomitans Porphyromonas gingivalis Prevotella intermedia Tannerella forsythia, and Treponema denticola. Correlations between the presence of periopathogens in sinus sites and periodontal pockets in adjacent teeth and the clinical findings (bone and implant survival) were studied. Results: A total of 23 patients were suitable for study inclusion. Periopathogens were found in sinus sites in 6 patients (26%) and in tooth sites in 15 patients (65%). There was low correlation for the presence of periopathogens between tooth sites and sinus sites and for complications. Conclusion: The presence of periopathogens as revealed by PCR was lower in sinus sites compared with tooth sites. Their presence neither caused bone pathology nor affected dental implant survival. The presence of periopathogens in sinus sites is inevitable even under periodontal maintenance. Although its presence did not endanger implant survival, future studies are recommended for studying this issue.

Original languageEnglish
Pages (from-to)913-919
Number of pages7
JournalInternational Journal of Oral and Maxillofacial Implants
Issue number5
StatePublished - 2022


  • Actinobacillus actinomycetemcomitans
  • Bacteria
  • Bacteroides gingivalis
  • Prevotella intermedia
  • Sinus augmentation sites
  • Tannerella forsythia
  • Treponema denticola

All Science Journal Classification (ASJC) codes

  • Oral Surgery


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