Plasmid evolution

Tanita Wein, Tal Dagan

Research output: Contribution to journalComment/debatepeer-review

Abstract

Plasmids are genetic elements that colonize and replicate in prokaryotic cells (Box 1). They are considered a major driving force of prokaryote evolution, as they can migrate between populations, making them potent agents of lateral DNA transfer and microbial warfare. The importance of plasmids goes beyond microbial evolution, as they are widely used as vectors for genetic engineering in basic research (e.g., random mutagenesis) as well as applications in biotechnology (e.g., insulin production), synthetic biology, agriculture (e.g., genetic engineering of crops) and medicine (e.g., biopharmaceuticals).

Original languageEnglish
Pages (from-to)R1158-R1163
JournalCurrent Biology
Volume30
Issue number19
DOIs
StatePublished - 5 Oct 2020
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Neuroscience
  • General Biochemistry,Genetics and Molecular Biology
  • General Agricultural and Biological Sciences

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