Piezoelectric Self-assembling Peptides for Engineering Applications

Haoran Wu, Sarah Guerin, Syed A.M. Tofail, Rusen Yang, Ehud Gazit, Damien Thompson, Kai Tao

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Piezoelectricity is undergoing a paradigm shift from traditional nonrecyclable, inorganic materials to eco-friendly, biodegradable analogues with desirable biocompatibility and multifunctionality. In this regard, the piezoelectric self-assembling peptides may be promising electromechanical coupling elements for diverse advanced bioelectronic devices, offering the modulated electromechanical properties required for next-generation implantable and wearable bioelectronic devices along with biocompatibility and biodegradability. Correspondingly, the piezoelectric response of peptide-based supramolecular architectures is being intensively studied. In this chapter, we provide a summary of the explored-to-date piezoelectric self-assembling peptides including monopeptides (amino acids), short peptides, and polypeptides/proteins, discussing the piezoelectric mechanisms and relevant applications in diverse arenas. We expect that this review can behave as a guideline for beginners in peptide piezoelectricity as well as researchers from tangential fields to incorporate functional peptide architectonics for sustainable devices developments.

Original languageEnglish
Title of host publicationPeptide Self-Assembly and Engineering
Subtitle of host publicationFundamentals, Structures, and Applications: Volume 1-2
Number of pages26
ISBN (Electronic)9783527841264
StatePublished - 1 Jan 2024


  • biointegrated microdevices
  • peptides
  • piezoelectricity
  • self-assembly

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering
  • General Biochemistry,Genetics and Molecular Biology


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