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Phenotypic Screen Identifies JAK2 as a Major Regulator of FAT10 Expression
Nava Reznik
, Avital Eisenberg-Lerner
,
Yifat Merbl
,
Nir London
Department of Systems Immunology
Weizmann Institute of Science
Research output
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peer-review
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Keyphrases
Janus Kinase 2 (JAK2)
100%
FAT10
100%
Phenotypic Screening
100%
Inflammatory Cytokines
25%
In Cancer
12%
Biological Role
12%
Pro-tumorigenic
12%
Tumor Necrosis Factor-α
12%
Inflammatory Process
12%
Cancer Development
12%
Knockdown
12%
Proteasomal Degradation
12%
Nuclear factor-κB
12%
Cell Regulation
12%
Interferon-γ
12%
JAK2 Inhibitor
12%
Ubiquitin-like
12%
Epithelial Cancer
12%
Transcriptional Effects
12%
Cytokine Induction
12%
Biochemical Control
12%
Tool Compound
12%
AZ960
12%
Transcriptional Reporter
12%
Biochemistry, Genetics and Molecular Biology
Janus Kinase
100%
Proinflammatory Cytokine
66%
Tumor Necrosis Factor Alpha
33%
Transcription
33%
Ubiquitin
33%
Immunoglobulin Enhancer Binding Protein
33%