Phase Transition Biopolymers and Methods of Use

Ashutosh Chilkoti; Felipe Garcia Quiroz; Miriam Amiram

Phase Transition Biopolymers and Methods of Use

Ashutosh Chilkoti (Inventor), Felipe Garcia Quiroz (Inventor), Miriam Amiram (Inventor)

Department of Biotechnology Engineering

Ben-Gurion University of the Negev

Research output: Patent

Abstract

The present disclosure describes environmentally responsive polypeptides capable of displaying stimuli-triggered conformational changes in a reversible or irreversible manner that may be accompanied by aggregation. Polypeptides include a number of repeated motifs and may be elastomeric or non-elastomeric. The polypeptides may be used to deliver therapeutics to a biological site and to develop bioactive polypeptides that are environmentally responsive.

Original language	American English
Patent number	US20180037609A1
State	Published - 1 Feb 2018

Cite this

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title = "Phase Transition Biopolymers and Methods of Use",

abstract = "The present disclosure describes environmentally responsive polypeptides capable of displaying stimuli-triggered conformational changes in a reversible or irreversible manner that may be accompanied by aggregation. Polypeptides include a number of repeated motifs and may be elastomeric or non-elastomeric. The polypeptides may be used to deliver therapeutics to a biological site and to develop bioactive polypeptides that are environmentally responsive.",

author = "Ashutosh Chilkoti and Quiroz, {Felipe Garcia} and Miriam Amiram",

note = "US Patent App. 15/679,751; US20180037609A1",

year = "2018",

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day = "1",

language = "American English",

type = "Patent",

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T1 - Phase Transition Biopolymers and Methods of Use

AU - Chilkoti, Ashutosh

AU - Quiroz, Felipe Garcia

AU - Amiram, Miriam

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PY - 2018/2/1

Y1 - 2018/2/1

N2 - The present disclosure describes environmentally responsive polypeptides capable of displaying stimuli-triggered conformational changes in a reversible or irreversible manner that may be accompanied by aggregation. Polypeptides include a number of repeated motifs and may be elastomeric or non-elastomeric. The polypeptides may be used to deliver therapeutics to a biological site and to develop bioactive polypeptides that are environmentally responsive.

AB - The present disclosure describes environmentally responsive polypeptides capable of displaying stimuli-triggered conformational changes in a reversible or irreversible manner that may be accompanied by aggregation. Polypeptides include a number of repeated motifs and may be elastomeric or non-elastomeric. The polypeptides may be used to deliver therapeutics to a biological site and to develop bioactive polypeptides that are environmentally responsive.

M3 - Patent

M1 - US20180037609A1

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