Peptides that target protein-protein interactions as an anti-parasite strategy

Research output: Contribution to journalArticlepeer-review

Abstract

Parasitic diseases are responsible for significant morbidity and mortality among vulnerable populations in developing countries where poor sanitation and lack of access to health care foster disease transmission. Current drugs are not sustainable for long-term treatment due to high toxicity, resistance issues, prohibitive prices, or inadequate methods of administration. There is an urgent need for new therapeutics that will address these issues. This mini-review discusses the potential of targeting therapeutically relevant protein-protein interactions with peptide inhibitors as anti-parasite drugs.

Original languageEnglish
Pages (from-to)31-36
Number of pages6
JournalChimica Oggi
Volume32
Issue number6
StatePublished - 1 Nov 2014
Externally publishedYes

Keywords

  • Anti-parasite therapeutic
  • Parasites
  • Parasitic diseases
  • Peptides
  • Protein-protein interactions

All Science Journal Classification (ASJC) codes

  • General Chemistry

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