Abstract
Biochemical pathways analysis is an effective tool for understanding changes in gene expression data and associating such changes with cellular phenotypes. Pathway research aims to identify associated proteins within a cell using pathways and at building new pathways from a group of molecules of interest. Using pathway-based methods we gain insight into different functions of relevant molecules and find direct and indirect relations between them. We present PathWeigh, a Python-based tool for pathway analysis and graph presentation. The tool is open-sourced, extendable and runtime efficient. PathWeigh is available at https://github.org/zurkin1/Pathweigh and is released under MIT license. A sample Python notebook is provided with examples of running the tool.
Original language | English |
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Title of host publication | Bioinformatics and Biomedical Engineering - 9th International Work-Conference, IWBBIO 2022, Proceedings |
Editors | Ignacio Rojas, Olga Valenzuela, Fernando Rojas, Luis Javier Herrera, Francisco Ortuño |
Publisher | Springer Science and Business Media Deutschland GmbH |
Pages | 346-352 |
Number of pages | 7 |
ISBN (Print) | 9783031078019 |
DOIs | |
State | Published - 2022 |
Event | 9th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2022 - Gran Canaria, Spain Duration: 27 Jun 2022 → 30 Jun 2022 |
Publication series
Name | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
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Volume | 13347 LNBI |
Conference
Conference | 9th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2022 |
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Country/Territory | Spain |
City | Gran Canaria |
Period | 27/06/22 → 30/06/22 |
Keywords
- Machine learning
- Pathway analysis
- RNA sequencing
All Science Journal Classification (ASJC) codes
- Theoretical Computer Science
- General Computer Science