Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O-2: a facile protocol to selectively synthesize 2-and 3-vinylindoles: a facile protocol to selectively synthesize 2- and 3-vinylindoles

Bo Cao; Marwan Simaan; Ilan Marek; Yin Wei; Min Shi

doi:10.1039/c6cc08731k

Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O-2: a facile protocol to selectively synthesize 2-and 3-vinylindoles: a facile protocol to selectively synthesize 2- and 3-vinylindoles

Bo Cao, Marwan Simaan, Ilan Marek, Yin Wei, Min Shi

Technion - Israel Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

A novel palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes using molecular oxygen as the terminal oxidant through β-carbon elimination of aminopalladation intermediates is disclosed. The reaction opens up an effective way to obtain a series of 2- and 3-vinylindoles which are important synthetic intermediates in many natural indole derivatives.

Original language	English
Pages (from-to)	216-219
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	1
DOIs	https://doi.org/10.1039/c6cc08731k
State	Published - 4 Jan 2017

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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title = "Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O-2: a facile protocol to selectively synthesize 2-and 3-vinylindoles: a facile protocol to selectively synthesize 2- and 3-vinylindoles",

abstract = "A novel palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes using molecular oxygen as the terminal oxidant through β-carbon elimination of aminopalladation intermediates is disclosed. The reaction opens up an effective way to obtain a series of 2- and 3-vinylindoles which are important synthetic intermediates in many natural indole derivatives.",

author = "Bo Cao and Marwan Simaan and Ilan Marek and Yin Wei and Min Shi",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2017",

month = jan,

day = "4",

doi = "10.1039/c6cc08731k",

language = "الإنجليزيّة",

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Cao, B, Simaan, M, Marek, I, Wei, Y & Shi, M 2017, 'Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O-2: a facile protocol to selectively synthesize 2-and 3-vinylindoles: a facile protocol to selectively synthesize 2- and 3-vinylindoles', Chemical Communications, vol. 53, no. 1, pp. 216-219. https://doi.org/10.1039/c6cc08731k

Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O-2: a facile protocol to selectively synthesize 2-and 3-vinylindoles: a facile protocol to selectively synthesize 2- and 3-vinylindoles. / Cao, Bo; Simaan, Marwan; Marek, Ilan et al.
In: Chemical Communications, Vol. 53, No. 1, 04.01.2017, p. 216-219.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O-2: a facile protocol to selectively synthesize 2-and 3-vinylindoles

T2 - a facile protocol to selectively synthesize 2- and 3-vinylindoles

AU - Cao, Bo

AU - Simaan, Marwan

AU - Marek, Ilan

AU - Wei, Yin

AU - Shi, Min

PY - 2017/1/4

Y1 - 2017/1/4

N2 - A novel palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes using molecular oxygen as the terminal oxidant through β-carbon elimination of aminopalladation intermediates is disclosed. The reaction opens up an effective way to obtain a series of 2- and 3-vinylindoles which are important synthetic intermediates in many natural indole derivatives.

AB - A novel palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes using molecular oxygen as the terminal oxidant through β-carbon elimination of aminopalladation intermediates is disclosed. The reaction opens up an effective way to obtain a series of 2- and 3-vinylindoles which are important synthetic intermediates in many natural indole derivatives.

UR - http://www.scopus.com/inward/record.url?scp=85006957555&partnerID=8YFLogxK

U2 - 10.1039/c6cc08731k

DO - 10.1039/c6cc08731k

M3 - مقالة

SN - 1359-7345

VL - 53

SP - 216

EP - 219

JO - Chemical Communications

JF - Chemical Communications

IS - 1

ER -

Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O-2: a facile protocol to selectively synthesize 2-and 3-vinylindoles: a facile protocol to selectively synthesize 2- and 3-vinylindoles

Abstract

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