Overtone Spectroscopy for Sensing-Recent Advances and Perspectives

Alina Karabchevsky, Uzziel Sheintop, Aviad Katiyi

Research output: Contribution to journalReview articlepeer-review


In this perspective, we report an opinion on overtone spectroscopy for sensing and discuss the nature of the opportunities perceived for specialists. New spectroscopic strategies can potentially be extended to detect other common toxic byproducts in a chip-scale label-free manner and to enhance the functionality of chemical and biological monitoring. Nevertheless, the full potential of overtone spectroscopy is not yet exhausted, challenges must be overcome, and new avenues await. Within this Perspective, we look at where the field currently stands, highlight several successful examples of overtone spectroscopy based sensors and detectors, and ask what it will take to advance current state-of-the-art technology. It is our intention to point out some potential blind spots and to inspire further developments.

Original languageAmerican English
Pages (from-to)2797-2803
Number of pages7
JournalACS Sensors
Issue number10
StatePublished - 28 Oct 2022


  • integrated photonics
  • molecular overtones
  • near-infrared spectroscopy
  • optical waveguide
  • sensing

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Instrumentation
  • Fluid Flow and Transfer Processes
  • Process Chemistry and Technology


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