@inbook{15cb82de1d664a6f9609ea7e2dff8962,
title = "Overhauser Dynamic Nuclear Polarization Studies on Local Water Dynamics",
abstract = "Overhauser dynamic nuclear polarization (ODNP) is an emerging technique for quantifying translational water dynamics in the vicinity (< 1 nm) of stable radicals that can be chemically attached to macromolecules of interest. This has led to many in-depth and enlightening studies of hydration water of biomolecules, revolving around the role of solvent dynamics in the structure and function of proteins, nucleic acids, and lipid bilayer membranes. Still to date, a complete and fully automated ODNP instrument is not commercialized. The purpose of this chapter is to share the technical know-how of the hardware, theory, measurement, and data analysis method needed to successfully utilize and disseminate the ODNP technique.",
keywords = "Hydration dynamics, Overhauser dynamic nuclear polarization, Protein hydration water measurements, Site-directed hydration dynamics, Site-directed spin labeling",
author = "Ilia Kaminker and Ryan Barnes and Songi Han",
note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",
year = "2015",
doi = "https://doi.org/10.1016/bs.mie.2015.06.040",
language = "الإنجليزيّة",
series = "Methods in Enzymology",
publisher = "Academic Press Inc.",
pages = "457--483",
booktitle = "Methods in Enzymology",
address = "الولايات المتّحدة",
}