Optimal allocation designs for a multi-arm multi-objective clinical trial

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Clinical trials have typically several goals, which can be divided into two types. The first type concerns the future patients that could potentially benefit from the treatments under consideration, and the second pertains to the health of the patients in the trial. For the former, it is important to correctly identify the best treatment, while the latter emphasizes the ethical requirements of the trial. This conflict is called “individual versus collective ethics” in Baldi Antognini and Giovagnoli [4], and “treatment versus experimentation dilemma” in Bartroff and Lai [5] and Azriel, Mandel and Rinott [1].

Original languageEnglish
Title of host publicationModern Adaptive Randomized Clinical Trials
Subtitle of host publicationStatistical and Practical Aspects
Number of pages19
ISBN (Electronic)9781482239898
StatePublished - 1 Jan 2015

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • General Medicine
  • General Mathematics


Dive into the research topics of 'Optimal allocation designs for a multi-arm multi-objective clinical trial'. Together they form a unique fingerprint.

Cite this