TY - JOUR
T1 - On the involvement of proteins in the assembly of the crayfish gastrolith extracellular matrix
AU - Glazer, Lilah
AU - Sagi, Amir
N1 - Funding Information: We thank Prof. Hans Laufer for inviting us to write this article as part of the proceedings of the symposium on: Biochemistry and Molecular Biology of Molting in Crustacaea and Insects, in the International Conference on Invertebrate Reproduction and Development in the Age of Genetic Modifications. We also thank Ms Katya Rechav for her assistance in operating the SEM and the acquisition of high-quality images, Dr Eli Aflalo for his assistance with the histological preparation, and Ms Inez Mureinik for styling the manuscript. The authors’ laboratory was supported in part by Israel Science Foundation Grant 1080/05, by German Israel Foundation Grant 950-9.5/2007, and by a grant from Amorphical Ltd.
PY - 2012/7/2
Y1 - 2012/7/2
N2 - It has been suggested that gastroliths are a good model for the study of biomineralization and extracellular organic matrix assembly, since they can serve as simplified cases of more complex mineralized biological structures, such as cuticles, bone, and teeth. Proteins are known to be key players in biomineralized chitinous matrices in general and in gastrolith assembly in particular. Here, we present a structural model that is based on the integration into the gastrolith assembly of the gastrolith proteins identified thus far. The model allows the assignment of these proteins to the different aspects of gastrolith construction, based on their characteristics. The model also predicts the existence of several additional proteins yet to be identified.
AB - It has been suggested that gastroliths are a good model for the study of biomineralization and extracellular organic matrix assembly, since they can serve as simplified cases of more complex mineralized biological structures, such as cuticles, bone, and teeth. Proteins are known to be key players in biomineralized chitinous matrices in general and in gastrolith assembly in particular. Here, we present a structural model that is based on the integration into the gastrolith assembly of the gastrolith proteins identified thus far. The model allows the assignment of these proteins to the different aspects of gastrolith construction, based on their characteristics. The model also predicts the existence of several additional proteins yet to be identified.
KW - Amorphous calcium carbonate
KW - Biomineralization
KW - Extracellular matrix
KW - Gastrolith proteins
UR - http://www.scopus.com/inward/record.url?scp=84862581363&partnerID=8YFLogxK
U2 - https://doi.org/10.1080/07924259.2011.588010
DO - https://doi.org/10.1080/07924259.2011.588010
M3 - Article
SN - 0792-4259
VL - 56
SP - 57
EP - 65
JO - Invertebrate Reproduction and Development
JF - Invertebrate Reproduction and Development
IS - 1
ER -