Omics approaches for subcellular translation studies

Indrek Koppel, Mike Fainzilber

Research output: Contribution to journalReview articlepeer-review


Compartmentalized translation allows rapid synthesis of proteins in targeted cellular locations. Microarray and RNA sequencing combined with physical subcellular separation methods have enabled extensive charting of subcellular transcriptomes. However, the extent of translating these local messages into protein remains relatively understudied at the genome-wide level. Here we review omics methods currently available for these studies, placing special attention on methods allowing cell-specific and subcellularly restricted analysis.

Original languageEnglish
Pages (from-to)380-388
Number of pages9
JournalMolecular Omics
Issue number6
Early online date10 Oct 2018
StatePublished - Dec 2018

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Genetics
  • Molecular Biology


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