NON-CYTOTOXIC MODIFIED CELLS AND USE THEREOF

Alon Monsonego (Inventor), Angel Porgador (Inventor), Roee Atlas (Inventor)

Research output: Patent

Abstract

Modified cells comprising a transmembrane polypeptide comprising at least one extracellular target receptor-binding domain, a transmembrane domain and an intracellular domain, wherein said intracellular domain is not capable of transducing any signal are provided. Methods of inducing or inhibiting signaling by a target receptor in a target cell comprising contacting the target cell with a modified cell of the invention are also provided.

Original languageAmerican English
Patent numberWO2018069927
IPCC12N 5/ 10 A I
Priority date10/10/16
StatePublished - 19 Apr 2018

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