TY - JOUR
T1 - New spatiotemporal approaches for fully refocused, multislice ultrafast 2D MRI
AU - Schmidt, Rita
AU - Frydman, Lucio
N1 - Kamin-Yeda Project (Israel Ministry of Trade and Industry) [711237]; ERC [246754]; DIP Collaborative Project (Federal German Ministry for Education and Research) [710907]; Helen and Martin Kimmel Award for Innovative Investigation; Perlman Family FoundationGrant sponsor: Kamin-Yeda Project (Israel Ministry of Trade and Industry); Grant number: 711237; Grant sponsor: ERC Advanced; Grant number: 246754; Grant sponsor: DIP Collaborative Project (Federal German Ministry for Education and Research); Grant number: 710907; Grant sponsor: Helen and Martin Kimmel Award for Innovative Investigation; Grant sponsor: Perlman Family Foundation.
PY - 2014/2
Y1 - 2014/2
N2 - Purpose Single-scan multislice acquisition schemes play key roles in magnetic resonance imaging. Central among these "ultrafast" experiments stands echo-planar imaging, a technique that although of optimal sampling is challenged by T2* artifacts. Recent studies described alternatives based on spatiotemporal encoding (SPEN), which are particularly robust if implemented in a "full-refocusing" mode. This work extends this modality from the single-slice acquisitions in which it has hitherto been implemented, by introducing a variety of multislice schemes scanning 3D volumes. Methods Multislice SPEN employing either inversion or stimulated echo pulses and timed to fulfill the demands of full refocusing, are demonstrated. The performance of the ensuing methods was examined in "Hybrid" modalities encoding data in k- and direct-space, in low-specific absorption rate stimulated-echo approaches, and in direct-space SPEN approaches. Results When applied in phantoms and in in vivo systems, the ensuing single-shot sequences evidenced similar robustness, sensitivity, and resolution qualities as previously discussed 2D single-slice schemes, while enabling a rapid sampling of the third dimension via multislicing. Conclusion The unique benefits deriving from fully refocused, multislice, single-scan SPEN sequences were corroborated by phantom tests, as well as by in vivo scans at 3 and 7 T. Low specific absorption rate multislice SPEN variants compatible with human studies were demonstrated.
AB - Purpose Single-scan multislice acquisition schemes play key roles in magnetic resonance imaging. Central among these "ultrafast" experiments stands echo-planar imaging, a technique that although of optimal sampling is challenged by T2* artifacts. Recent studies described alternatives based on spatiotemporal encoding (SPEN), which are particularly robust if implemented in a "full-refocusing" mode. This work extends this modality from the single-slice acquisitions in which it has hitherto been implemented, by introducing a variety of multislice schemes scanning 3D volumes. Methods Multislice SPEN employing either inversion or stimulated echo pulses and timed to fulfill the demands of full refocusing, are demonstrated. The performance of the ensuing methods was examined in "Hybrid" modalities encoding data in k- and direct-space, in low-specific absorption rate stimulated-echo approaches, and in direct-space SPEN approaches. Results When applied in phantoms and in in vivo systems, the ensuing single-shot sequences evidenced similar robustness, sensitivity, and resolution qualities as previously discussed 2D single-slice schemes, while enabling a rapid sampling of the third dimension via multislicing. Conclusion The unique benefits deriving from fully refocused, multislice, single-scan SPEN sequences were corroborated by phantom tests, as well as by in vivo scans at 3 and 7 T. Low specific absorption rate multislice SPEN variants compatible with human studies were demonstrated.
UR - http://www.scopus.com/inward/record.url?scp=84892438407&partnerID=8YFLogxK
U2 - https://doi.org/10.1002/mrm.24714
DO - https://doi.org/10.1002/mrm.24714
M3 - مقالة
SN - 0740-3194
VL - 71
SP - 711
EP - 722
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 2
ER -