Nanotechnology meets electrophysiology

Recording of electrical signals from electrogenic cells is an essential aspect to many areas, ranging from fundamental biophysical studies of the function of the brain and heart, through medical monitoring and intervention. Over the past decades, these studies have been primarily carried out by various well-established techniques that have greatly advanced the field, yet pose handicapping technical limitations. Nanotechnologyallows the fabrication of devices small enough to enable recording of single cells, and even single neurites. The rise in knowledge in controlling nanostructures allows their tailoring to match cellular components, thus offering high level of interfacing to single cells. We will cover the latest developments in electrophysiology, applying new nanotechnology-based approaches for cellular electrical recordings, both extracellularly and intracellularly.