Abstract
Nanoplasmonic biosensors based on gold nanoparticle functionalized smooth silica and porous calcium carbonate particles are presented. It is identified in this comparative study the role of porosity for adsorbing gold nanoparticles and subsequent detection of biomarkers. That is further applied in this study for detection of biomarkers. Detection of glucose - a biomarker of diabetes is studied together with that of bovine serum albumin - a very relevant bio-molecule. Raman scattering is used for label-free detection of molecules in the sub-μM-mM range detection capabilities, which covers the range corresponding to healthy and diseased persons. Implications of current study for detection and identification of biomarkers are discussed. Nanoplasmonic biosensors based on gold nanoparticle functionalized smooth silica and porous calcium carbonate particles is presented. In this comparative study the role of porosity for adsorbing gold nanoparticles and the subsequent detection of biomarkers is identified.
| Original language | English |
|---|---|
| Pages (from-to) | 723-732 |
| Number of pages | 10 |
| Journal | Annalen der Physik |
| Volume | 524 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2012 |
| Externally published | Yes |
Keywords
- Nanoplasmonic
- Raman
- SERS
- beads
- biomarkers
- calcium carbonate
- porous
All Science Journal Classification (ASJC) codes
- General Physics and Astronomy
