Nanoparticles for imaging, sensing, and therapeutic intervention

Lara K. Bogart; Genevieve Pourroy; Catherine J. Murphy; Victor Puntes; Teresa Pellegrino; Daniel Rosenblum; Dan Peer; Raphaël Lévy

doi:https://doi.org/10.1021/nn500962q

Nanoparticles for imaging, sensing, and therapeutic intervention

Lara K. Bogart, Genevieve Pourroy, Catherine J. Murphy, Victor Puntes, Teresa Pellegrino, Daniel Rosenblum, Dan Peer, Raphaël Lévy

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.

Original language	English
Pages (from-to)	3107-3122
Number of pages	16
Journal	ACS Nano
Volume	8
Issue number	4
DOIs	https://doi.org/10.1021/nn500962q
State	Published - 22 Apr 2014

All Science Journal Classification (ASJC) codes

General Engineering
General Materials Science
General Physics and Astronomy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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https://doi.org/10.1021/nn500962q

Cite this

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abstract = "Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.",

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AU - Bogart, Lara K.

AU - Pourroy, Genevieve

AU - Murphy, Catherine J.

AU - Puntes, Victor

AU - Pellegrino, Teresa

AU - Rosenblum, Daniel

AU - Peer, Dan

AU - Lévy, Raphaël

PY - 2014/4/22

Y1 - 2014/4/22

N2 - Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.

AB - Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.

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EP - 3122

JO - ACS Nano

JF - ACS Nano

IS - 4

ER -

Nanoparticles for imaging, sensing, and therapeutic intervention

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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