Abstract
Dual action: Trackable multifunctional dendritic scaffolds with high internal loading capacity were synthesized based on a PEG core. Orthogonal functionalization of chain-end and internal groups allowed the dendrimers to be both labeled and loaded with releasable dyes for simultaneous monitoring of the dendritic carrier and release of the dye payload inside living cells (see picture).
Original language | English |
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Pages (from-to) | 3425-3429 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 50 |
Issue number | 15 |
DOIs | |
State | Published - 4 Apr 2011 |
Externally published | Yes |
Keywords
- click chemistry
- delivery platforms
- dendrimers
- dye tracking
- fluorescence microscopy
All Science Journal Classification (ASJC) codes
- General Chemistry
- Catalysis