@article{5c8e265ae693421c86ba394ee03a2fde,
title = "Moving from probiotics to precision probiotics",
abstract = "A precision approach to probiotics could address the heterogeneity inherent to probiotic strains, the hosts and their microbiomes. Here, we discuss the steps required to develop precision probiotics: mechanistic studies, phenotypic and target-based discovery strategies, and person-centric trials.",
author = "Patrick Veiga and Jotham Suez and Muriel Derrien and Eran Elinav",
note = "We thank the members of the Elinav laboratory and members of the DKFZ Cancer-Microbiome division for discussions. We apologize to authors whose work was not included due to space constraints. We also thank L. Jimenez, S. Miret-Catalan and D. Obis (members of Danone Nutricia Research) for the discussions. E.E. is supported by: Y. and R. Ungar; the Abisch Frenkel Foundation for the Promotion of Life Sciences; the Gurwin Family Fund for Scientific Research; the Leona M. and Harry B. Helmsley Charitable Trust; the Crown Endowment Fund for Immunological Research; the Else Kroener Fresenius Foundation; the estate of J. Gitlitz; the estate of L. Hershkovich; the Benoziyo Endowment Fund for the Advancement of Science; the Adelis Foundation; J. L. and V. Schwartz; A. and G. Markovitz; A. and C. Adelson; the French National Center for Scientific Research (CNRS); D. L. Schwarz; the V. R. Schwartz Research Fellow Chair; L. Steinberg; J. N. Halpern; A. Edelheit; and by grants funded by the European Research Council, the Israel Science Foundation and the Helmholtz Foundation. E.E. is the Sir Marc \& Lady Tania Feldmann Professorial Chair in Immunology at the Weizmann Institute of Science, the Director of the Microbiome Research Division at DKFZ, is a senior fellow of the Canadian Institute of Advanced Research (CIFAR) and an international scholar of the Bill \& Melinda Gates Foundation and Howard Hughes Medical Institute (HHMI). P.V., M.D., J.S. and E.E. wrote the manuscript.",
year = "2020",
month = may,
day = "11",
doi = "10.1038/s41564-020-0721-1",
language = "الإنجليزيّة",
volume = "5",
pages = "878--880",
journal = "Nature Microbiology",
issn = "2058-5276",
publisher = "Nature Research",
number = "7",
}