Molecular mechanism for the function of bacteriorhodopsin and visual pigments: Studies with model compounds and artificial pigments

Mordechai Sheves; Michael Ottolenghi

doi:10.1201/9781351070638

Molecular mechanism for the function of bacteriorhodopsin and visual pigments: Studies with model compounds and artificial pigments

Mordechai Sheves, Michael Ottolenghi

Department of Molecular Chemistry and Materials Science

Weizmann Institute of Science

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The visual process is initiated via light absorption by rhodopsin (Rh) pigments consisting of a retinyl polyene chromophore (11-cis) covalently bound to a membrane apo-protein (opsin) through a protonated Schiff base linkage with a lysine residue. 1-4 Excitation leads to changes in the electrical potential of the membrane, which are transmitted to the brain through appropriate synaptic processes.

Original language	English
Title of host publication	Chemistry and Biology of Synthetic Retinoids
Publisher	CRC Press
Chapter	5
Pages	99-124
Number of pages	26
ISBN (Electronic)	9781351079082
ISBN (Print)	0849347971, 9781315891538
DOIs	https://doi.org/10.1201/9781351070638
State	Published - 22 Dec 2018

All Science Journal Classification (ASJC) codes

General Medicine
General Biochemistry,Genetics and Molecular Biology

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10.1201/9781351070638

Cite this

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Molecular mechanism for the function of bacteriorhodopsin and visual pigments: Studies with model compounds and artificial pigments

Abstract

All Science Journal Classification (ASJC) codes

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