Abstract

This volume covers an array of techniques available for studying peptide-protein docking and design. The book is divided into four sections: peptide binding site prediction; peptide-protein docking; prediction and design of peptide binding specificity; and the design of inhibitory peptides. The chapters in Modeling Peptide-Protein Interactions: Methods and Protocols cover topics such as the usage of ACCLUSTER and PeptiMap for peptide binding site prediction; AnchorDock and ATTRACT for blind, flexible docking of peptides to proteins; flexible peptide docking using HADDOCK and FlexPepDock; identifying loop-mediated protein-protein interactions using LoopFinder; and protein-peptide interaction design using PinaColada. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary details for successful application of the different approaches and step-by-step, readily reproducible protocols, as well as tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Modeling Peptide-Protein Interactions: Methods and Protocols provides a diverse and unified overview of this rapidly advancing field of major interest and applicability.
Original languageEnglish
Place of PublicationNew York, NY
Number of pages311
Edition1st ed. 2017
ISBN (Electronic)1493967983, 978-1-4939-6798-8
DOIs
StatePublished - 2017

Publication series

NameMethods in Molecular Biology
PublisherSpringer New York; Imprint: Humana
Volume1561

ULI publications

  • uli
  • Biochemistry
  • Biological chemistry
  • Chemical composition of organisms
  • Organisms -- Composition
  • Physiological chemistry
  • ביוכימיה

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