Micrornas: New players in multiple myeloma

Flavia Pichiorri; Luciana De Luca; Rami I. Aqeilan

doi:10.3389/fgene.2011.00022

Micrornas: New players in multiple myeloma

Flavia Pichiorri, Luciana De Luca, Rami I. Aqeilan

Department of Immunology and Cancer Research

The Hebrew University of Jerusalem

Research output: Contribution to journal › Article › peer-review

Abstract

MicroRNAs (miRNAs) are short non-coding RNAs that play critical roles in numerous cellular processes through post-transcriptional regulating functions. The aberrant role of miRNAs has been reported in a number of hematopoietic malignancies including multiple myeloma (MM). In this review we summarize the current knowledge on roles of miRNAs in the pathogenesis of MM.

Original language	English
Article number	Article 22
Journal	Frontiers in Genetics
Volume	2
Issue number	MAY
DOIs	https://doi.org/10.3389/fgene.2011.00022
State	Published - 2011

Keywords

MDM2
MiRNAs
Microarray
Multiple myeloma
P53
Profiling

All Science Journal Classification (ASJC) codes

Molecular Medicine
Genetics
Genetics(clinical)

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10.3389/fgene.2011.00022

Cite this

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title = "Micrornas: New players in multiple myeloma",

abstract = "MicroRNAs (miRNAs) are short non-coding RNAs that play critical roles in numerous cellular processes through post-transcriptional regulating functions. The aberrant role of miRNAs has been reported in a number of hematopoietic malignancies including multiple myeloma (MM). In this review we summarize the current knowledge on roles of miRNAs in the pathogenesis of MM.",

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author = "Flavia Pichiorri and \{De Luca\}, Luciana and Aqeilan, \{Rami I.\}",

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doi = "10.3389/fgene.2011.00022",

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AU - De Luca, Luciana

AU - Aqeilan, Rami I.

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Y1 - 2011

N2 - MicroRNAs (miRNAs) are short non-coding RNAs that play critical roles in numerous cellular processes through post-transcriptional regulating functions. The aberrant role of miRNAs has been reported in a number of hematopoietic malignancies including multiple myeloma (MM). In this review we summarize the current knowledge on roles of miRNAs in the pathogenesis of MM.

AB - MicroRNAs (miRNAs) are short non-coding RNAs that play critical roles in numerous cellular processes through post-transcriptional regulating functions. The aberrant role of miRNAs has been reported in a number of hematopoietic malignancies including multiple myeloma (MM). In this review we summarize the current knowledge on roles of miRNAs in the pathogenesis of MM.

KW - MDM2

KW - MiRNAs

KW - Microarray

KW - Multiple myeloma

KW - P53

KW - Profiling

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DO - 10.3389/fgene.2011.00022

M3 - مقالة

SN - 1664-8021

VL - 2

JO - Frontiers in Genetics

JF - Frontiers in Genetics

IS - MAY

M1 - Article 22

ER -

Micrornas: New players in multiple myeloma

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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