@article{fba209789ad444aeae48cd3b028b0b3d,
title = "Microglia Biology: One Century of Evolving Concepts",
abstract = "Microglia were first recognized as a distinct cell population in the CNS one century ago. For a long time, they were primarily considered to be phagocytes responsible for removing debris during CNS development and disease. More recently, advances in imaging and genetics and the advent of single-cell technology provided new insights into the much more complex and fascinatir; biology of microglia. The ontogeny of microglia was identified, and their functions in health and disease were better defined. Although many qL lions about microglia and their roles in human diseases remain unanswered, the prospect of targeting microglia for the treatment of neurological and psychiatric disorders is tantalizing.",
author = "Marco Prinz and Steffen Jung and Josef Priller",
note = "The authors are grateful to Takahiro Masuda for preparing the excellent figures. M.P. is supported by the Sobek Foundation, the Ernst Jung Foundation, the German Research Foundation (DFG) (SFB 992, SFB1160, and Reinhart Koselleck grant), the Ministry of Science, Research and Arts, Baden-Wuerttemberg (Sonderlinie “Neuroinflammation”), and the BMBF-funded Competence Network of Multiple Sclerosis (KKNMS). His research is supported by the DFG under Germany{\textquoteright}s Excellence Strategy (CIBSS – EXC-2189 – project ID 390939984). S.J. is supported by the Israeli Science Foundation (887/11), the European Research Council (Adv ERC 340345), and a collaborative network grant from the International Progressive MS Alliance (PMSA). J.P. is supported by the DFG SFB/TRR265, BMBF (AERIAL), BIH, DZNE, and the UK DRI (Momentum Award). M.P., S.J., and J.P. are all supported by DFG SFB/TRR167.",
year = "2019",
month = oct,
day = "3",
doi = "10.1016/j.cell.2019.08.053",
language = "الإنجليزيّة",
volume = "179",
pages = "292--311",
journal = "Cell",
issn = "0092-8674",
publisher = "Elsevier B.V.",
number = "2",
}