Microfluidic large scale integration of viral-host interaction analysis

Ya'Ara Ben-Ari; Yair Glick; Sarit Kipper; Nika Schwartz; Dorit Avrahami; Efrat Barbiro-Michaely; Doron Gerber

doi:https://doi.org/10.1039/c3lc00034f

Microfluidic large scale integration of viral-host interaction analysis

Ya'Ara Ben-Ari, Yair Glick, Sarit Kipper, Nika Schwartz, Dorit Avrahami, Efrat Barbiro-Michaely, Doron Gerber

The Mina and Everard Goodman Faculty of Life Sciences

Bar-Ilan University

Research output: Contribution to journal › Review article › peer-review

Abstract

Viral-host interactions represent potential drug targets for novel antiviral strategies (Flisiak et al., Hepatology, 2008, 47, 817-26). Hence, it is important to establish an adequate platform for identifying and analyzing such interactions. In this review, we discuss bottlenecks in conventional protein-protein interaction methodologies and present the contribution of innovative microfluidic-based technologies towards a solution to these problems with respect to viral-host proteomics.

Original language	English
Pages (from-to)	2202-2209
Number of pages	8
Journal	Lab on a Chip
Volume	13
Issue number	12
Early online date	20 Mar 2013
DOIs	https://doi.org/10.1039/c3lc00034f
State	Published - 21 Jun 2013

All Science Journal Classification (ASJC) codes

General Chemistry
Bioengineering
Biochemistry
Biomedical Engineering

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Cite this

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abstract = "Viral-host interactions represent potential drug targets for novel antiviral strategies (Flisiak et al., Hepatology, 2008, 47, 817-26). Hence, it is important to establish an adequate platform for identifying and analyzing such interactions. In this review, we discuss bottlenecks in conventional protein-protein interaction methodologies and present the contribution of innovative microfluidic-based technologies towards a solution to these problems with respect to viral-host proteomics.",

author = "Ya'Ara Ben-Ari and Yair Glick and Sarit Kipper and Nika Schwartz and Dorit Avrahami and Efrat Barbiro-Michaely and Doron Gerber",

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AU - Ben-Ari, Ya'Ara

AU - Glick, Yair

AU - Kipper, Sarit

AU - Schwartz, Nika

AU - Avrahami, Dorit

AU - Barbiro-Michaely, Efrat

AU - Gerber, Doron

PY - 2013/6/21

Y1 - 2013/6/21

N2 - Viral-host interactions represent potential drug targets for novel antiviral strategies (Flisiak et al., Hepatology, 2008, 47, 817-26). Hence, it is important to establish an adequate platform for identifying and analyzing such interactions. In this review, we discuss bottlenecks in conventional protein-protein interaction methodologies and present the contribution of innovative microfluidic-based technologies towards a solution to these problems with respect to viral-host proteomics.

AB - Viral-host interactions represent potential drug targets for novel antiviral strategies (Flisiak et al., Hepatology, 2008, 47, 817-26). Hence, it is important to establish an adequate platform for identifying and analyzing such interactions. In this review, we discuss bottlenecks in conventional protein-protein interaction methodologies and present the contribution of innovative microfluidic-based technologies towards a solution to these problems with respect to viral-host proteomics.

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U2 - https://doi.org/10.1039/c3lc00034f

DO - https://doi.org/10.1039/c3lc00034f

M3 - مقالة مرجعية

C2 - 23645014

SN - 1473-0197

VL - 13

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EP - 2209

JO - Lab on a Chip

JF - Lab on a Chip

IS - 12

ER -

Microfluidic large scale integration of viral-host interaction analysis

Abstract

All Science Journal Classification (ASJC) codes

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