Metabolic sensing tips the balance of drug tolerance in fungal meningitis

Austin Mottola; Johannes Hartl; Markus Ralser; Judith Berman

doi:https://doi.org/10.1038/s41564-023-01595-5

Metabolic sensing tips the balance of drug tolerance in fungal meningitis

Austin Mottola, Johannes Hartl, Markus Ralser, Judith Berman

The Shmunis School of Biomedicine and Cancer Research

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

Sensing of brain glucose by the fungal pathogen Cryptococcus neoformans alters lipid metabolism and membrane composition in the fungus, rendering it drug tolerant.

Original language	English
Pages (from-to)	316-317
Number of pages	2
Journal	Nature Microbiology
Volume	9
Issue number	2
DOIs	https://doi.org/10.1038/s41564-023-01595-5
State	Published - Feb 2024

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Applied Microbiology and Biotechnology
Genetics
Microbiology (medical)
Cell Biology

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https://doi.org/10.1038/s41564-023-01595-5

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title = "Metabolic sensing tips the balance of drug tolerance in fungal meningitis",

abstract = "Sensing of brain glucose by the fungal pathogen Cryptococcus neoformans alters lipid metabolism and membrane composition in the fungus, rendering it drug tolerant.",

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Metabolic sensing tips the balance of drug tolerance in fungal meningitis

Abstract

All Science Journal Classification (ASJC) codes

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