Abstract
Lilium candidum L., known as Madonna, meadow, or white lily, is a bulbous plant from the Liliaceae family, originating in the Middle East. L. candidum has been abundantly used in folk medicine since ancient times to relieve a variety of ailments, including age-related diseases, burns, ulcers, and coughs. The aim of this article is to investigate the anti-inflammatory and anti-diabetic activities of L. candidum extracts and its active phytochemicals. Some active volatile phytochemicals were identified using gas chromatography–mass spectrometry (GC-MS) analysis. Significant (p < 0.001) anti-diabetic properties of the extracts kaempferol, linalool, citronellal, and humulene were demonstrated by an elevation in glucose uptake by adipocytes. The significant (p < 0.01) effect of the plant extracts kaempferol, citronellal, and humulene on the secretion of pro-inflammatory cytokines interleukin 6 (IL-6) and interleukin 8 (IL-8) was demonstrated using enzyme-linked immunosorbent assay. Altogether, L. candidum and its rich collection of phytochemicals hold promising medicinal potential, and further investigations of its therapeutic prospects are encouraged.
| Original language | English |
|---|---|
| Article number | 959 |
| Pages (from-to) | 1-11 |
| Number of pages | 11 |
| Journal | Plants |
| Volume | 9 |
| Issue number | 8 |
| DOIs | |
| State | Published - 1 Aug 2020 |
Keywords
- Lilium candidum
- Medicinal activities
- Phytochemicals
All Science Journal Classification (ASJC) codes
- Ecology, Evolution, Behavior and Systematics
- Ecology
- Plant Science
