Medication Detection by a Combinatorial Fluorescent Molecular Sensor

Bhimsen Rout; Linor Unger; Gad Armony; Mark A. Iron; David Margulies

doi:10.1002/anie.201206374

Medication Detection by a Combinatorial Fluorescent Molecular Sensor

Bhimsen Rout, Linor Unger, Gad Armony, Mark A. Iron, David Margulies

Weizmann Institute of Science

Research output: Contribution to journal › Article › peer-review

Abstract

Working together to uncover the truth: A molecule-sized diagnostic system combining several recognition elements and four fluorescence-emission channels enabled the identification of a wide range of pharmaceuticals on the basis of distinct photophysical processes. The molecular sensor (see simplified representation; ID=identification) was also used to analyze drug concentrations and combinations in urine samples in a high-throughput manner.

Original language	English
Pages (from-to)	12477-12481
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	50
DOIs	https://doi.org/10.1002/anie.201206374
State	Published - 7 Dec 2012

All Science Journal Classification (ASJC) codes

General Chemistry
Catalysis

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10.1002/anie.201206374

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title = "Medication Detection by a Combinatorial Fluorescent Molecular Sensor",

abstract = "Working together to uncover the truth: A molecule-sized diagnostic system combining several recognition elements and four fluorescence-emission channels enabled the identification of a wide range of pharmaceuticals on the basis of distinct photophysical processes. The molecular sensor (see simplified representation; ID=identification) was also used to analyze drug concentrations and combinations in urine samples in a high-throughput manner.",

author = "Bhimsen Rout and Linor Unger and Gad Armony and Iron, {Mark A.} and David Margulies",

note = "Peter and Patricia Gruber Foundation; Helen and Martin Kimmel Center for Molecular DesignThis research was supported by the Peter and Patricia Gruber Foundation and by the Helen and Martin Kimmel Center for Molecular Design. D. M. is the incumbent of the Judith and Martin Freedman Career Development Chair. We thank Dr. Leila Motiei for fruitful discussions.",

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doi = "10.1002/anie.201206374",

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AU - Rout, Bhimsen

AU - Unger, Linor

AU - Armony, Gad

AU - Iron, Mark A.

AU - Margulies, David

N1 - Peter and Patricia Gruber Foundation; Helen and Martin Kimmel Center for Molecular DesignThis research was supported by the Peter and Patricia Gruber Foundation and by the Helen and Martin Kimmel Center for Molecular Design. D. M. is the incumbent of the Judith and Martin Freedman Career Development Chair. We thank Dr. Leila Motiei for fruitful discussions.

PY - 2012/12/7

Y1 - 2012/12/7

N2 - Working together to uncover the truth: A molecule-sized diagnostic system combining several recognition elements and four fluorescence-emission channels enabled the identification of a wide range of pharmaceuticals on the basis of distinct photophysical processes. The molecular sensor (see simplified representation; ID=identification) was also used to analyze drug concentrations and combinations in urine samples in a high-throughput manner.

AB - Working together to uncover the truth: A molecule-sized diagnostic system combining several recognition elements and four fluorescence-emission channels enabled the identification of a wide range of pharmaceuticals on the basis of distinct photophysical processes. The molecular sensor (see simplified representation; ID=identification) was also used to analyze drug concentrations and combinations in urine samples in a high-throughput manner.

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DO - 10.1002/anie.201206374

M3 - مقالة

SN - 1433-7851

VL - 51

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EP - 12481

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 50

ER -

Medication Detection by a Combinatorial Fluorescent Molecular Sensor

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