Machine learning approaches to optimize small-molecule inhibitors for RNA targeting

Keyphrases

• Small Molecules 100%
• MiRNA Target 100%
• Data-driven Algorithm 100%
• Machine Learning Approach 100%
• Mycobacterium Tuberculosis (M. tb) 100%
• Small Molecule Inhibitors 100%
• Peptidyl Transferase Center 100%
• Potent Inhibitor 50%
• Chemical Space 50%
• Molecular Scaffold 50%
• Visual Features 50%
• Short Hairpin RNA (shRNA) 50%
• Geometrical Features 50%
• Chemical Features 50%
• Hairpin 50%
• Data Science 50%
• Science Data 50%
• Functional Validation 50%
• Phenylthiazole 50%
• Bioisosteric 50%

Biochemistry, Genetics and Molecular Biology

• RNA 100%
• Small Molecule 100%
• Peptidyl Transferase 66%
• Mycobacterium Tuberculosis 33%

Chemistry

• Ribonucleic Acid 100%
• Molecular Scaffold 33%