Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population

Muhammad Abu Tailakh; Liat Poupko; Najwan Kayyal; Ali Alsana; Asia Estis-Deaton; Ohad Etzion; Alexander Fich; David Yardni; Naim Abu-Freha

doi:10.1007/s10903-021-01263-y

Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population

Muhammad Abu Tailakh, Liat Poupko, Najwan Kayyal, Ali Alsana, Asia Estis-Deaton, Ohad Etzion, Alexander Fich, David Yardni, Naim Abu-Freha

Ben-Gurion University of the Negev

Research output: Contribution to journal › Article › peer-review

Abstract

Liver cirrhosis (LC) is a common disease with varied primary causes and ethnic disparities. Clinical characteristics and outcomes of Arab Bedouin (AB) and Jewish patients with LC were retrospective collected and compared. We included 1048 patients, 95 (9%) Arab Bedouin and 953 (91%) Jewish patients. The incidence of cirrhosis was much lower among AB. Age at diagnosis was 47 ± 18 years among Bedouins compared to 61 ± 13 years (p < 0.001) among Jews. The most frequent causes of cirrhosis among Bedouin patients were fatty liver 21.1%, cryptogenic 20%, hepatitis B 17.9% and autoimmune hepatitis 15.8%, while hepatitis C (39.2%), fatty liver (17.2%) and alcoholic liver disease (14.4%) were most common among Jewish patients. An all-cause mortality of 48.4% was observed in AB patients compared to 66.4% in Jewish patients (p < 0.001). Significant disparities regarding incidence, clinical characteristics and outcomes of cirrhosis among Arab Bedouin compared with Jewish population were found.

Original language	American English
Pages (from-to)	1122-1128
Number of pages	7
Journal	Journal of Immigrant and Minority Health
Volume	24
Issue number	5
DOIs	https://doi.org/10.1007/s10903-021-01263-y
State	Published - 1 Oct 2022

Keywords

Arab Bedouin
Cirrhosis
Complications
Jews
Mortality

All Science Journal Classification (ASJC) codes

Public Health, Environmental and Occupational Health
Epidemiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s10903-021-01263-y

Cite this

@article{6d5a3a0f8df64299a0cd71bb07270f7f,

title = "Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population",

abstract = "Liver cirrhosis (LC) is a common disease with varied primary causes and ethnic disparities. Clinical characteristics and outcomes of Arab Bedouin (AB) and Jewish patients with LC were retrospective collected and compared. We included 1048 patients, 95 (9%) Arab Bedouin and 953 (91%) Jewish patients. The incidence of cirrhosis was much lower among AB. Age at diagnosis was 47 ± 18 years among Bedouins compared to 61 ± 13 years (p < 0.001) among Jews. The most frequent causes of cirrhosis among Bedouin patients were fatty liver 21.1%, cryptogenic 20%, hepatitis B 17.9% and autoimmune hepatitis 15.8%, while hepatitis C (39.2%), fatty liver (17.2%) and alcoholic liver disease (14.4%) were most common among Jewish patients. An all-cause mortality of 48.4% was observed in AB patients compared to 66.4% in Jewish patients (p < 0.001). Significant disparities regarding incidence, clinical characteristics and outcomes of cirrhosis among Arab Bedouin compared with Jewish population were found.",

keywords = "Arab Bedouin, Cirrhosis, Complications, Jews, Mortality",

author = "Tailakh, {Muhammad Abu} and Liat Poupko and Najwan Kayyal and Ali Alsana and Asia Estis-Deaton and Ohad Etzion and Alexander Fich and David Yardni and Naim Abu-Freha",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2022",

month = oct,

day = "1",

doi = "10.1007/s10903-021-01263-y",

language = "American English",

volume = "24",

pages = "1122--1128",

journal = "Journal of Immigrant and Minority Health",

issn = "1557-1912",

publisher = "Springer New York",

number = "5",

}

TY - JOUR

T1 - Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population

AU - Tailakh, Muhammad Abu

AU - Poupko, Liat

AU - Kayyal, Najwan

AU - Alsana, Ali

AU - Estis-Deaton, Asia

AU - Etzion, Ohad

AU - Fich, Alexander

AU - Yardni, David

AU - Abu-Freha, Naim

PY - 2022/10/1

Y1 - 2022/10/1

N2 - Liver cirrhosis (LC) is a common disease with varied primary causes and ethnic disparities. Clinical characteristics and outcomes of Arab Bedouin (AB) and Jewish patients with LC were retrospective collected and compared. We included 1048 patients, 95 (9%) Arab Bedouin and 953 (91%) Jewish patients. The incidence of cirrhosis was much lower among AB. Age at diagnosis was 47 ± 18 years among Bedouins compared to 61 ± 13 years (p < 0.001) among Jews. The most frequent causes of cirrhosis among Bedouin patients were fatty liver 21.1%, cryptogenic 20%, hepatitis B 17.9% and autoimmune hepatitis 15.8%, while hepatitis C (39.2%), fatty liver (17.2%) and alcoholic liver disease (14.4%) were most common among Jewish patients. An all-cause mortality of 48.4% was observed in AB patients compared to 66.4% in Jewish patients (p < 0.001). Significant disparities regarding incidence, clinical characteristics and outcomes of cirrhosis among Arab Bedouin compared with Jewish population were found.

AB - Liver cirrhosis (LC) is a common disease with varied primary causes and ethnic disparities. Clinical characteristics and outcomes of Arab Bedouin (AB) and Jewish patients with LC were retrospective collected and compared. We included 1048 patients, 95 (9%) Arab Bedouin and 953 (91%) Jewish patients. The incidence of cirrhosis was much lower among AB. Age at diagnosis was 47 ± 18 years among Bedouins compared to 61 ± 13 years (p < 0.001) among Jews. The most frequent causes of cirrhosis among Bedouin patients were fatty liver 21.1%, cryptogenic 20%, hepatitis B 17.9% and autoimmune hepatitis 15.8%, while hepatitis C (39.2%), fatty liver (17.2%) and alcoholic liver disease (14.4%) were most common among Jewish patients. An all-cause mortality of 48.4% was observed in AB patients compared to 66.4% in Jewish patients (p < 0.001). Significant disparities regarding incidence, clinical characteristics and outcomes of cirrhosis among Arab Bedouin compared with Jewish population were found.

KW - Arab Bedouin

KW - Cirrhosis

KW - Complications

KW - Jews

KW - Mortality

UR - http://www.scopus.com/inward/record.url?scp=85113806097&partnerID=8YFLogxK

U2 - 10.1007/s10903-021-01263-y

DO - 10.1007/s10903-021-01263-y

M3 - Article

C2 - 34453643

SN - 1557-1912

VL - 24

SP - 1122

EP - 1128

JO - Journal of Immigrant and Minority Health

JF - Journal of Immigrant and Minority Health

IS - 5

ER -

Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population

Abstract

Keywords

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Cite this