Lessons from Animal Models of Arterial Aneurysm

S. David Gertz, Yoav Mintz, Ronen Beeri, Chen Rubinstein, Dan Gilon, Leah Gavish, Yacov Berlatzky, Liat Appelbaum, Lilach Gavish

Research output: Contribution to journalReview articlepeer-review

Abstract

We review the results from the most common animal models of arterial aneurysm, including recent findings from our novel, laparoscopy-based pig model of abdominal aortic aneurysm, that contribute important insights into early pathogenesis. We emphasize the relevance of these findings for evaluation of treatment protocols and novel device prototypes for mechanism-based prevention of progression and rupture.

Original languageEnglish
Pages (from-to)244-254
Number of pages11
JournalAORTA
Volume1
Issue number5
DOIs
StatePublished - 28 Oct 2013

Keywords

  • Abdominal aortic aneurysm
  • Animal models
  • Arterial aneurysm
  • Periarterial calcium chloride

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Radiology Nuclear Medicine and imaging

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