@inproceedings{4d560eeaf0ff4fa19ba0223f8eb8063a,
title = "Label-free optical-resolution photoacoustic endomicroscopy in vivo",
abstract = "Intravital microscopy techniques have become increasingly important in biomedical research because they can provide unique microscopic views of various biological or disease developmental processes in situ. Here we present an optical-resolution photoacoustic endomicroscopy (OR-PAEM) system that visualizes internal organs with a much finer resolution than conventional acoustic-resolution photoacoustic endoscopy systems. By combining gradient index (GRIN) lens-based optical focusing and ultrasonic ring transducer-based acoustic focusing, we achieved a transverse resolution as fine as ∼10 μm at an optical working distance of 6.5 mm. The OR-PAEM system's high-resolution intravital imaging capability is demonstrated through animal experiments.",
keywords = "In vivo imaging, Intravital microscopy, Label-free imaging, Optical-resolution, Photoacoustic endomicroscopy, Photoacoustic endoscopy, Photoacoustic microscopy, Rat colorectum",
author = "Yang, {Joon Mo} and Chiye Li and Ruimin Chen and Bin Rao and Junjie Yao and Yeh, {Cheng Hung} and Amos Danielli and Konstantin Maslov and Qifa Zhou and Shung, {K. Kirk} and Wang, {Lihong V.}",
note = "Publisher Copyright: {\textcopyright} 2015 SPIE.; Photons Plus Ultrasound: Imaging and Sensing 2015 ; Conference date: 08-02-2015 Through 10-02-2015",
year = "2015",
month = mar,
day = "11",
doi = "10.1117/12.2080224",
language = "الإنجليزيّة",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Oraevsky, {Alexander A.} and Wang, {Lihong V.}",
booktitle = "Photons Plus Ultrasound",
address = "الولايات المتّحدة",
}