Is cell size a spandrel?

Research output: Contribution to journalArticlepeer-review

Abstract

All organisms control the size of their cells. We focus here on the question of size regulation in bacteria, and suggest that the quantitative laws governing cell size and its dependence on growth rate may arise as byproducts of a regulatory mechanism which evolved to support multiple DNA replication forks. In particular, we show that the increase of bacterial cell size during Lenski’s long-term evolution experiments is a natural outcome of this proposal. This suggests that, in the context of evolution, cell size may be a ‘spandrel’.

Original languageEnglish
Article numbere22186
JournaleLife
Volume6
DOIs
StatePublished - 19 Jan 2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Immunology and Microbiology
  • General Biochemistry,Genetics and Molecular Biology
  • General Neuroscience

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