Abstract
Novel selective synthesis route to introduce primary alkyl groups on aromatic compounds is disclosed. The synthesis route is based on electrophilic aromatic substitutions of thionium ion species that are generated in-situ from aldehydes and thiols, affording benzyl sulfide that can be reduced with triethylsilane.
Original language | American English |
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Patent number | US2018065904 |
IPC | C07C 321/ 20 A I |
Priority date | 16/02/16 |
State | Published - 8 Mar 2018 |