Abstract
Regulatory T (Treg) cells lie in proximity to nerve fibers in the colon lamina propria. Yan et al. reveal a regulatory circuit wherein microbial signals condition neuronal density and activation, which in turn, via neuron-produced IL-6, tunes Treg cell generation, which has implications for intestinal tolerance.
Original language | English |
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Pages (from-to) | 499-513.e5 |
Journal | Immunity (Cambridge, Mass.) |
Volume | 54 |
Issue number | 3 |
DOIs | |
State | Published - 9 Mar 2021 |
All Science Journal Classification (ASJC) codes
- Infectious Diseases
- Immunology and Allergy
- Immunology