Abstract
In 2008, an increase in the prevalence of carbapenem- resistant Klebsiella pneumoniae was noted in a 286- bed tertiary case hospital in Colombia, where 84 patients (32 infected and 52 colonized) had positive cultures. The identified index patient came from Israel for a liver transplantation. High level carbapenem resistance was observed. Polymyxin B and tigecycline were the only two antibiotics that remained active. PCR- restriction fragment length polymorphism analysis and sequencing revealed blaKPC- 3 in the major clone, which was indistinguishable from the K. pneumoniae carbapenemase- 3- producing clone described previously in Israel. This exemplifies the threat posed by the global spread of K. pneumoniae carbapenemase- producing pathogens.
Original language | English |
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Pages (from-to) | 52-56 |
Number of pages | 5 |
Journal | Clinical Microbiology and Infection |
Volume | 17 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2011 |
Externally published | Yes |
Keywords
- Colombia
- Dissemination
- Israel
- KPC- 3
- Klebsiella pneumoniae
All Science Journal Classification (ASJC) codes
- Microbiology (medical)
- Infectious Diseases