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Integration of porous silicon-based optical aptasensors in a 3d-printed microfluidic platform for protein detection

  • Sofia Arshavsky-Graham
  • , Niklas Maximilian Epping
  • , Anton Enders
  • , Thomas Scheper
  • , Janina Bahnemann
  • , Ester Segal

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The paper presents the integration of optical aptasensors with a 3D-printed microfluidic platform and demonstrates their improved performance. Porous silicon (PSi)-based aptasensors for specific detection of a model target protein are interfaced with acrylic 3D-printed microchannels via a UV-curable adhesive. The resulting platform is shown to allow real-time and label-free target detection with enhanced sensitivity by at least an order of magnitude.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Pages1078-1079
Number of pages2
ISBN (Electronic)9781733419000
StatePublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: 27 Oct 201931 Oct 2019

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Country/TerritorySwitzerland
CityBasel
Period27/10/1931/10/19

Keywords

  • 3D Printing
  • Aptamer
  • Biosensor
  • Microfluidic
  • Porous Silicon

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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