@article{aa02cb12aa9a42d89cd9f3fdfc7eaf4d,
title = "Inflammation-induced cancer: Crosstalk between tumours, immune cells and microorganisms",
abstract = "Inflammation is a fundamental innate immune response to perturbed tissue homeostasis. Chronic inflammatory processes affect all stages of tumour development as well as therapy. In this Review, we outline the principal cellular and molecular pathways that coordinate the tumour-promoting and tumour-antagonizing effects of inflammation and we discuss the crosstalk between cancer development and inflammatory processes. In addition, we discuss the recently suggested role of commensal microorganisms in inflammationinduced cancer and we propose that understanding this microbial influence will be crucial for targeted therapy in modern cancer treatment.",
author = "Eran Elinav and Roni Nowarski and Thaiss, {Christoph A.} and Bo Hu and Chengcheng Jin and Flavell, {Richard A.}",
note = "Marie Curie Integration and Helmsley Charitable Foundation; Howard Hughes Medical Institute; US Department of Defense [11-1-0745]; United States-Israel Binational Foundation grant; Boehinger Ingelheim Fonds Ph.D. Fellowship; Jane Coffin Childs Memorial Fund; Yale University, USAThe authors thank all members of the Elinav and Flavell laboratories for scientific suggestions and discussion. This work was supported by the Marie Curie Integration and Helmsley Charitable Foundation grants (to E.E.), by the Howard Hughes Medical Institute and a grant from the US Department of Defense 11-1-0745 (to R.A.F.) and a United States-Israel Binational Foundation grant (to E.E. and R.A.F.). C.A.T. receives a Boehinger Ingelheim Fonds Ph.D. Fellowship. R.N. is supported by a fellowship from the Jane Coffin Childs Memorial Fund, and C.J. was a recipient of a Trudeau Fellowship from Yale University, USA.",
year = "2013",
doi = "https://doi.org/10.1038/nrc3611",
language = "الإنجليزيّة",
volume = "13",
pages = "759--771",
journal = "Nature Reviews Cancer",
issn = "1474-175X",
publisher = "Nature Publishing Group",
number = "11",
}