In vitro fertilization informed consent: Revisited, empirically

Ilona Voskoboynikov-Ugortsev, Yaakov Rosenfeld, Lital Keinan Boker

Research output: Contribution to journalReview articlepeer-review


Background: A thorough informed consent (IC) process is required before in vitro fertilization (IVF) treatments can begin because these treatments are by and large elective and they have expectable and preventable complications, such as ovarian hyper-stimulation syndrome and multi-fetal pregnancies. Objectives: To empirically examine whether patient knowledge and understanding of potential hazards associated with IVF treatment are better after the IC process compared to before. The authors hypothesized that patients' better understanding of potential complications would be translated and expressed as rational choices of treatment alternatives. Methods: Responses of 48 IVF patients after IC process (study group) from two IVF units in northern Israel were compared to those of 46 patients before IVF (control group). Only women undergoing IVF for first time who were older than 18 years of age were eligible for the study. Results: Socio-demographic parameters were found to be quite similar between the study group and the control group. Contrary to our expectations, in the study group 12 women (25.5%) considered delivery of a single baby as their optimal result, compared to 15 (32.6%) in the control group. Furthermore, preferences shifted toward triplets: eight patients (17%) after IC considered this option as their best result, compared to only five patients (11%) before IC. Conclusions: IC process goals are not achieved under current practices, at least as far as IVF treatment are concerned. New tools and incentives should be implemented to meet the requirements dictated by the laws regarding patient rights.

Original languageAmerican English
Pages (from-to)681-683
Number of pages3
JournalIsrael Medical Association Journal
Issue number11
StatePublished - Nov 2020


  • Adult
  • Comprehension
  • Female
  • Fertilization in Vitro/adverse effects
  • Humans
  • In vitro fertilization
  • Informed Consent/legislation & jurisprudence
  • Informed consent
  • Israel
  • Ovarian Hyperstimulation Syndrome/etiology
  • Pregnancy
  • Pregnancy, Multiple/statistics & numerical data
  • Surveys and Questionnaires
  • Young Adult

All Science Journal Classification (ASJC) codes

  • General Medicine


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