Identification of Mycobacterium pseudoshottsii in the Eastern Mediterranean

Nadav Davidovich, Andrei Makhon, Gal Zizelski Valenci, Zeev Dveyrin, Tal Yahav, Tobia Pretto, Dan Tchernov, Danny Morick

Research output: Contribution to journalArticlepeer-review


Among the numerous pathogenic nontuberculous mycobacteria (NTM), which may cause disease in both poikilothermic and homoeothermic organisms, members of the unique clade Mycobacterium ulcerans/Mycobacterium marinum (MuMC) may cause disease in both fish and humans. Here, we describe the emergence of Mycobacterium pseudoshottsii, one of the four MuMC members, in Israel. For many years, M. marinum was the dominant NTM that was diagnosed in Israel as a fish pathogen. To the best of our knowledge, this is the first isolation and genomic characterization of M. pseudoshottsii infecting edible fish from two different fish species farmed in offshore sea cages in the eastern Mediterranean as well as in a recirculating aquaculture system in Israel. We compared the M. pseudoshottsii whole-genome sequences to all available genomic sequences of MuMC in free, publicly accessible databases.

Original languageAmerican English
JournalMicrobiology spectrum
Issue number4
StatePublished - 17 Aug 2023


  • Israel
  • Mycobacterium pseudoshottsii
  • emerging pathogen
  • nontuberculous mycobacteria

All Science Journal Classification (ASJC) codes

  • General Immunology and Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Genetics
  • Physiology
  • Cell Biology
  • Ecology


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