Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease

Sophie Schonauer, Heinz G. Koerschen, Anke Penno, Andreas Rennhack, Bernadette Breiden, Konrad Sandhoff, Katharina Gutbrod, Peter Dormann, Diana N. Raju, Per Haberkant, Mathias J. Gerl, Britta Bruegger, Hila Zigdon, Ayelet Vardi, Anthony H. Futerman, Christoph Thiele, Dagmar Wachten

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Medicine & Life Sciences

Chemistry