Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

Jean-Nicolas Dumez Dumez, Jonas Milani, B Vuichoud, A Bornet, Julie Lalande-Martin, Illa Tea, Maxime Yon, M Maucourt, C Deborde, A Moing, Lucio Frydman, G Bodenhausen, Sami Jannin, P Giraudeau

Research output: Contribution to journalArticlepeer-review

Abstract

Natural abundance 13C NMR spectra of biological extracts are recorded in a single scan provided that the samples are hyperpolarized by dissolution dynamic nuclear polarization combined with cross polarization. Heteronuclear 2D correlation spectra of hyperpolarized breast cancer cell extracts can also be obtained in a single scan. Hyperpolarized NMR of extracts opens many perspectives for metabolomics.

Original languageEnglish
Pages (from-to)5860-5863
Number of pages4
JournalAnalyst
Volume140
Issue number17
DOIs
StatePublished - 7 Sep 2015

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Spectroscopy
  • Electrochemistry
  • Environmental Chemistry

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