Huntingtin facilitates selective autophagy

Amir Gelman; Slobodkin, Moran Rawet Slobodkin; Zvulun Elazar

doi:10.1038/ncb3125

Huntingtin facilitates selective autophagy

Amir Gelman, Slobodkin, Moran Rawet Slobodkin, Zvulun Elazar

Department of Biomolecular Sciences

Weizmann Institute of Science

Research output: Contribution to journal › Short survey › peer-review

Abstract

Selective autophagy is essential for maintaining cellular homeostasis under different growth conditions. Huntingtin, mutated versions of which have been implicated in Huntington disease, is now shown to act as a scaffold protein that couples the induction of autophagy and the selective recruitment of cargo into autophagosomes.

Original language	English
Pages (from-to)	214-215
Number of pages	2
Journal	Nature Cell Biology
Volume	17
Issue number	3
Early online date	27 Feb 2015
DOIs	https://doi.org/10.1038/ncb3125
State	Published - Mar 2015

All Science Journal Classification (ASJC) codes

Cell Biology

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10.1038/ncb3125

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title = "Huntingtin facilitates selective autophagy",

abstract = "Selective autophagy is essential for maintaining cellular homeostasis under different growth conditions. Huntingtin, mutated versions of which have been implicated in Huntington disease, is now shown to act as a scaffold protein that couples the induction of autophagy and the selective recruitment of cargo into autophagosomes.",

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Huntingtin facilitates selective autophagy

Abstract

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