Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Pierre Bost; Amir Giladi; Yang Liu; Yanis Bendjelal; Gang Xu; Eyal David; Ronnie Blecher-Gonen; Merav Cohen; Chiara Medaglia; Hanjie Li; Aleksandra Deczkowska; Shuye Zhang; Benno Schwikowski; Zheng Zhang; Ido Amit

doi:10.1016/j.cell.2020.05.006

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Pierre Bost, Amir Giladi, Yang Liu, Yanis Bendjelal, Gang Xu, Eyal David, Ronnie Blecher-Gonen, Merav Cohen, Chiara Medaglia, Hanjie Li, Aleksandra Deczkowska, Shuye Zhang, Benno Schwikowski, Zheng Zhang, Ido Amit

Research output: Contribution to journal › Article › peer-review

Abstract

A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.

Original language	English
Pages (from-to)	1475-1488.e12
Journal	Cell
Volume	181
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2020.05.006
State	Published - 25 Jun 2020
Externally published	Yes

Keywords

COVID-19
Viral-Track
single-cell RNA-seq
virus host interactions

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.cell.2020.05.006

Cite this

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title = "Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients",

abstract = "A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.",

keywords = "COVID-19, Viral-Track, single-cell RNA-seq, virus host interactions",

author = "Pierre Bost and Amir Giladi and Yang Liu and Yanis Bendjelal and Gang Xu and Eyal David and Ronnie Blecher-Gonen and Merav Cohen and Chiara Medaglia and Hanjie Li and Aleksandra Deczkowska and Shuye Zhang and Benno Schwikowski and Zheng Zhang and Ido Amit",

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year = "2020",

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day = "25",

doi = "10.1016/j.cell.2020.05.006",

language = "الإنجليزيّة",

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journal = "Cell",

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TY - JOUR

T1 - Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

AU - Bost, Pierre

AU - Giladi, Amir

AU - Liu, Yang

AU - Bendjelal, Yanis

AU - Xu, Gang

AU - David, Eyal

AU - Blecher-Gonen, Ronnie

AU - Cohen, Merav

AU - Medaglia, Chiara

AU - Li, Hanjie

AU - Deczkowska, Aleksandra

AU - Zhang, Shuye

AU - Schwikowski, Benno

AU - Zhang, Zheng

AU - Amit, Ido

PY - 2020/6/25

Y1 - 2020/6/25

N2 - A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.

AB - A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.

KW - COVID-19

KW - Viral-Track

KW - single-cell RNA-seq

KW - virus host interactions

UR - http://www.scopus.com/inward/record.url?scp=85085276687&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.05.006

DO - 10.1016/j.cell.2020.05.006

M3 - مقالة

C2 - 32479746

SN - 0092-8674

VL - 181

SP - 1475-1488.e12

JO - Cell

JF - Cell

IS - 7

ER -

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Abstract

Keywords

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

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