Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Pierre Bost; Amir Giladi; Yang Liu; Yanis Bendjelal; Gang Xu; Eyal David; Ronnie Blecher-Gonen; Merav Cohen; Chiara Medaglia; Hanjie Li; Aleksandra Deczkowska; Shuye Zhang; Benno Schwikowski; Zheng Zhang; Ido Amit

doi:10.1016/j.cell.2020.05.006

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Pierre Bost, Amir Giladi, Yang Liu, Yanis Bendjelal, Gang Xu, Eyal David, Ronnie Blecher-Gonen, Merav Cohen, Chiara Medaglia, Hanjie Li, Aleksandra Deczkowska, Shuye Zhang, Benno Schwikowski, Zheng Zhang, Ido Amit

Research output: Contribution to journal › Article › peer-review

Abstract

A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.

Original language	English
Pages (from-to)	1475-1488.e12
Journal	Cell
Volume	181
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2020.05.006
State	Published - 25 Jun 2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19
Viral-Track
single-cell RNA-seq
virus host interactions

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology

Access to Document

10.1016/j.cell.2020.05.006

Cite this

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title = "Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients",

abstract = "A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.",

keywords = "COVID-19, Viral-Track, single-cell RNA-seq, virus host interactions",

author = "Pierre Bost and Amir Giladi and Yang Liu and Yanis Bendjelal and Gang Xu and Eyal David and Ronnie Blecher-Gonen and Merav Cohen and Chiara Medaglia and Hanjie Li and Aleksandra Deczkowska and Shuye Zhang and Benno Schwikowski and Zheng Zhang and Ido Amit",

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year = "2020",

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day = "25",

doi = "10.1016/j.cell.2020.05.006",

language = "الإنجليزيّة",

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journal = "Cell",

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TY - JOUR

T1 - Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

AU - Bost, Pierre

AU - Giladi, Amir

AU - Liu, Yang

AU - Bendjelal, Yanis

AU - Xu, Gang

AU - David, Eyal

AU - Blecher-Gonen, Ronnie

AU - Cohen, Merav

AU - Medaglia, Chiara

AU - Li, Hanjie

AU - Deczkowska, Aleksandra

AU - Zhang, Shuye

AU - Schwikowski, Benno

AU - Zhang, Zheng

AU - Amit, Ido

PY - 2020/6/25

Y1 - 2020/6/25

N2 - A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.

AB - A computational framework that allows for the identification and characterization of virus-infected cells as well as bystander cell responses reveals how SARS-CoV-2 alters the immune responses of patients.

KW - COVID-19

KW - Viral-Track

KW - single-cell RNA-seq

KW - virus host interactions

UR - http://www.scopus.com/inward/record.url?scp=85085276687&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.05.006

DO - 10.1016/j.cell.2020.05.006

M3 - مقالة

C2 - 32479746

SN - 0092-8674

VL - 181

SP - 1475-1488.e12

JO - Cell

JF - Cell

IS - 7

ER -

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Abstract

UN SDGs

Keywords

All Science Journal Classification (ASJC) codes

Access to Document

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