Abstract
Patients with Gaucher disease suffering from the consequences of femoral head osteonecrosis deserve a treatment modality that will eliminate pain, preserve ambulation and hopefully will endure long enough to allow satisfactory daily life. Total hip arthroplasty fulfills these 3 objectives. The rate of complications during anesthesia and during surgical procedure is comparable to otherwise healthy population if the Gaucher patients are carefully evaluated pre-surgery and prepared by a medical team familiar with all aspects of the disease. With prompt preparation, meticulous procedure, and careful post-operative care, patients with Gaucher disease may benefit from long-lasting hip prostheses. It is to be hoped that newer types of implants would allow longer revision-free periods even in this young patient population who have developed avascular necrosis, and a greater hope for patients with Gaucher disease would be that early administration of bone-specific therapies may prevent osteonecrosis.
| Original language | English |
|---|---|
| Pages (from-to) | 60-65 |
| Number of pages | 6 |
| Journal | Blood Cells, Molecules, and Diseases |
| Volume | 46 |
| Issue number | 1 |
| DOIs | |
| State | Published - 15 Jan 2011 |
| Externally published | Yes |
Keywords
- Arthroplasty
- Avascular necrosis
- Enzyme replacement therapy
- Gaucher disease
- Hip replacement
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Molecular Biology
- Hematology
- Cell Biology
Fingerprint
Dive into the research topics of 'Hip arthroplasty in patients with Gaucher disease'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver