Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling

Nicolas Panayotis; Mike Fainzilber

doi:10.1016/j.neuron.2019.04.019

Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling

Nicolas Panayotis
, Mike Fainzilber

Department of Biomolecular Sciences

Weizmann Institute of Science

Research output: Contribution to journal › Review article › peer-review

Abstract

In this issue of Neuron, Crerar et al. (2019) found Tp53inp2 as a highly expressed RNA in sympathetic neuron axons. Strikingly, its long 3′ UTR ensures that Tp53inp2 is not translated in axons, and the untranslated RNA affects neuronal growth by interacting with neurotrophin receptors.

Original language	English GB
Pages (from-to)	507-509
Number of pages	3
Journal	Neuron
Volume	102
Issue number	3
DOIs	https://doi.org/10.1016/j.neuron.2019.04.019
State	Published - 8 May 2019

ASJC Scopus subject areas

General Neuroscience

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title = "Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling",

abstract = "In this issue of Neuron, Crerar et al. (2019) found Tp53inp2 as a highly expressed RNA in sympathetic neuron axons. Strikingly, its long 3′ UTR ensures that Tp53inp2 is not translated in axons, and the untranslated RNA affects neuronal growth by interacting with neurotrophin receptors.",

author = "Nicolas Panayotis and Mike Fainzilber",

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doi = "10.1016/j.neuron.2019.04.019",

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AU - Fainzilber, Mike

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N2 - In this issue of Neuron, Crerar et al. (2019) found Tp53inp2 as a highly expressed RNA in sympathetic neuron axons. Strikingly, its long 3′ UTR ensures that Tp53inp2 is not translated in axons, and the untranslated RNA affects neuronal growth by interacting with neurotrophin receptors.

AB - In this issue of Neuron, Crerar et al. (2019) found Tp53inp2 as a highly expressed RNA in sympathetic neuron axons. Strikingly, its long 3′ UTR ensures that Tp53inp2 is not translated in axons, and the untranslated RNA affects neuronal growth by interacting with neurotrophin receptors.

UR - https://www.scopus.com/pages/publications/85064281881

U2 - 10.1016/j.neuron.2019.04.019

DO - 10.1016/j.neuron.2019.04.019

M3 - مقالة مرجعية

SN - 0896-6273

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SP - 507

EP - 509

JO - Neuron

JF - Neuron

IS - 3

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Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling

Abstract

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