Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens

Eran Gutman; Yael Litvak

doi:10.1016/j.chom.2024.04.011

Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens

Eran Gutman
, Yael Litvak

The Hebrew University of Jerusalem

Research output: Contribution to journal › Comment/debate

Abstract

Common nutrients in our diet often affect our health through unexpected mechanisms. In a recent issue of Nature, Scott et al. show gut microbes convert dietary tryptophan into metabolites activating intestinal dopamine receptors, which can block attachment of bacterial pathogens to host cells.

Original language	English
Pages (from-to)	623-624
Number of pages	2
Journal	Cell Host and Microbe
Volume	32
Issue number	5
DOIs	https://doi.org/10.1016/j.chom.2024.04.011
State	Published - 8 May 2024

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

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10.1016/j.chom.2024.04.011

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title = "Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens",

abstract = "Common nutrients in our diet often affect our health through unexpected mechanisms. In a recent issue of Nature, Scott et al. show gut microbes convert dietary tryptophan into metabolites activating intestinal dopamine receptors, which can block attachment of bacterial pathogens to host cells.",

author = "Eran Gutman and Yael Litvak",

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year = "2024",

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TY - JOUR

T1 - Gut dopamine kick

T2 - How gut microbes turn on host receptors to fight pathogens

AU - Gutman, Eran

AU - Litvak, Yael

PY - 2024/5/8

Y1 - 2024/5/8

N2 - Common nutrients in our diet often affect our health through unexpected mechanisms. In a recent issue of Nature, Scott et al. show gut microbes convert dietary tryptophan into metabolites activating intestinal dopamine receptors, which can block attachment of bacterial pathogens to host cells.

AB - Common nutrients in our diet often affect our health through unexpected mechanisms. In a recent issue of Nature, Scott et al. show gut microbes convert dietary tryptophan into metabolites activating intestinal dopamine receptors, which can block attachment of bacterial pathogens to host cells.

UR - https://www.scopus.com/pages/publications/85191960743

U2 - 10.1016/j.chom.2024.04.011

DO - 10.1016/j.chom.2024.04.011

M3 - Comment/debate

C2 - 38723597

SN - 1931-3128

VL - 32

SP - 623

EP - 624

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 5

ER -

Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens

Abstract

ASJC Scopus subject areas

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