@inproceedings{3be9bc115c184bae82151b6f4d9334ab,
title = "Gold nanoparticles for safe delivery of cisplatin",
abstract = "Cisplatin (CP) is the primary standard treatment for bladder cancer. Nevertheless, CP has side effects, particularly nephrotoxicity. This limits the treatment of a notable portion of advanced bladder cancer patients with cisplatin. We have developed gold nanoparticles that conjugate CP (CP-AuNPs) for safer delivery to tumors. Here, we investigated the biodistribution of the CP-AuNP conjugates in a mouse model of bladder cancer, to characterize the distinct role of CPAuNP in delivering and releasing CP in tumor and tissues. Effect of the CP-AuNPs on weight and kidney was also investigated. This study can provide insights into the potential safety of CP-AuNP for bladder cancer treatment.",
keywords = "biodistribution, cancer, cisplatin-gold nanoparticles",
author = "Yoray Sharon and Menachem Motiei and Chen Tzror-Azankot and Tamar Sadan and Rachela Popovtzer and Eli Rosenbaum",
note = "Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI 2024 ; Conference date: 28-01-2024",
year = "2024",
doi = "10.1117/12.3005425",
language = "الإنجليزيّة",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Dror Fixler and Sebastian Wachsmann-Hogiu",
booktitle = "Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI",
address = "الولايات المتّحدة",
}
