Glycan Microarray Reveal the Sweet Side of Cancer Vaccines

Vered Padler-Karavani

doi:10.1016/j.chembiol.2016.12.002

Glycan Microarray Reveal the Sweet Side of Cancer Vaccines

Vered Padler-Karavani

Department of Cell Research and Immunology

Tel Aviv University

Research output: Contribution to journal › Short survey › peer-review

Abstract

Advances in genomics and bioinformatics facilitated identification of tumor-specific neoantigens as optimal targets for cancer immunotherapy. In this hot topic, most efforts focus on mutant peptide antigens, overlooking tumor-associated glycosylation changes. Given the latest progress in glycomics, in this issue of Cell Chemical Biology, Xia et al. (2016) use glyco-antigen microarrays to investigate immune responses to whole cancer vaccines and provide important insights into vaccine efficacy.

Original language	English
Pages (from-to)	1446-1447
Number of pages	2
Journal	Cell Chemical Biology
Volume	23
Issue number	12
DOIs	https://doi.org/10.1016/j.chembiol.2016.12.002
State	Published - 22 Dec 2016

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmacology
Drug Discovery
Clinical Biochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.chembiol.2016.12.002

Cite this

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title = "Glycan Microarray Reveal the Sweet Side of Cancer Vaccines",

abstract = "Advances in genomics and bioinformatics facilitated identification of tumor-specific neoantigens as optimal targets for cancer immunotherapy. In this hot topic, most efforts focus on mutant peptide antigens, overlooking tumor-associated glycosylation changes. Given the latest progress in glycomics, in this issue of Cell Chemical Biology, Xia et al. (2016) use glyco-antigen microarrays to investigate immune responses to whole cancer vaccines and provide important insights into vaccine efficacy.",

author = "Vered Padler-Karavani",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Ltd",

year = "2016",

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AB - Advances in genomics and bioinformatics facilitated identification of tumor-specific neoantigens as optimal targets for cancer immunotherapy. In this hot topic, most efforts focus on mutant peptide antigens, overlooking tumor-associated glycosylation changes. Given the latest progress in glycomics, in this issue of Cell Chemical Biology, Xia et al. (2016) use glyco-antigen microarrays to investigate immune responses to whole cancer vaccines and provide important insights into vaccine efficacy.

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Glycan Microarray Reveal the Sweet Side of Cancer Vaccines

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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